P4 Medicine – Predictive, Preventative, Personalized, Participatory – is where healthcare is headed. In the near term, as the bulk of the population ages, there will still be a large portion of the industry devoted to treating disease. But more and more of medicine’s focus will be on neutralizing problems before they occur. Advances in genomics, imaging and diagnostic tools will enable this. Medical device designers will have a big part to play, because imaging devices will get smaller to the point of being hand-held. This will require smart application of human factors knowledge. Diagnostic devices also will be increasingly brought into field clinics and into the home, where good ergonomics and ease of use are especially important. The use of microfluidic technology in diagnostic devices will have huge impact in the developing world. In such devices, simplicity and ease of use will again be paramount. The P4 future is rapidly approaching, and medical device designers will be an important part of it.